Newborn Screening for Cystic Fibrosis was introduced in The Netherlands in 2011. Parents, who have a child diagnosed with Cystic Fibrosis, are faced with a sudden and impactful life event that evokes anxiety and stress. A parental coaching program was set up by the Dutch Cystic Fibrosis Foundation in order to support the parents. Feasibility and possible effects of the program were studied in a pilot. The program seems to have positive effects on the psychological wellbeing of the parents. After the intervention, levels of anxiety and distress of the parents significantly decreased, compared to the start of the program. Overall, the program was rated very positively by the participants and 90% stated they reached their personal predefined goals. Both the structure and content of the program are feasible for them. They would highly advise the program to future parents with a child diagnosed with CF